At the World AMR Congress, Recce Pharmaceuticals contributes by making strides with a synthetic compound designed to target bacterial mutations, underscoring the need for innovation in addressing antimicrobial resistance (AMR). “Our compound is entirely synthetic,” Graham said. “We started with first principles, designing a compound that remains effective with repeated use.”
The new antibiotic functions as a broad-spectrum solution, targeting bacteria across various infections without distinguishing between ‘good’ and ‘bad’ bacteria. “Bacteria mutate continuously, but our compound remains effective regardless of these mutations. It functions as a broad-spectrum antibiotic, targeting bacteria across various infections, such as UTIs, without distinguishing between ‘good’ and ‘bad’ bacteria. This allows us to work faster and more effectively than other antibiotics. Our compound empowers clinicians to treat patients quickly and reliably, even with repeated use.”
Graham addressed current gaps in AMR awareness, noting that the industry often repeats existing strategies while expecting different results. “We have approached this challenge differently by exploring polymeric chemistry, creating a compound that remains effective and soluble across various pH levels, including those found in the blood and stomach. The industry must innovate rather than reiterate existing methods. The market recognizes and rewards genuine innovation that delivers substantial value.”
On market adoption, Graham highlighted the challenges of introducing novel treatments and strategies to bring new antimicrobial treatments to market to become broadly adopted. “Bringing anything new to market is challenging, especially with novel compounds. The more innovative a product, the more hesitant the industry can be.”
The development process includes identifying and patenting the optimal compound, navigating regulatory cycles from preclinical to clinical trials, and achieving real-world clinical outcomes.
Graham discusses the stages of product development:
Identifying and patenting the optimal compound,
Navigating the regulatory cycle from preclinical to clinical trials
Achieving real-world clinical outcomes.
Successfully completing these stages drives investor and commercial interest. Reece Pharmaceuticals’ efforts significantly advance AMR treatment, aiming to provide effective solutions for critical infections.
This website may contain affiliate links and advertising so that we can provide recipes to you. Read my disclosure policy.
Enjoy juicy, ripe peaches in this No-Bake Fresh Peach Pie. It has a creamy cheesecake filling topped with sweet peaches, all nestled in a buttery graham cracker crust. It’s so delicious and the best part is that no baking is required!
Reasons You’ll Love This Recipe
Simple: This fresh peach pie recipe requires just a handful of simple ingredients and only takes 20 minutes to whip up!
Delicious Flavors and Textures: The combination of peaches and cream with a buttery graham cracker crust is out of this world!
Quick and Easy to Prep: No baking required for this recipe! It’s perfect for a make-ahead summer dessert!
No Bake Peach Pie Ingredients
The ingredients needed to make this no-bake peach pie recipe are simple and minimal. If you’re in a pinch and need to save some time, you can use a store-bought graham cracker crust. However, it won’t have the same rich, buttery crunch. For exact measurements, scroll to the recipe card below.
Graham Cracker Crust
Graham Cracker Crumbs: You’ll need 1 ½ cups graham cracker crumbs, which is about 12 whole graham crackers.
Granulated Sugar: To sweeten the crust.
Salt: Balances the sweet flavor.
Salted Butter: Binds the crust together while adding buttery flavor.
Cream Filling
Cream Cheese: Provides the creamy, tangy base of the filling.
Granulated Sugar: To sweeten the filling.
Vanilla Extract: Adds a hint of sweet, warm vanilla flavor.
Frozen Whipped Topping: Makes the creamy filling light and fluffy.
Peach Topping
Fresh Peaches: The star of this pie! If you love the flavor of sweet, juicy peaches, you will love this pie!
Brown Sugar: Adds sweetness and balances any tart taste from the peaches.
Lemon Juice: Brightens the flavor of the peaches.
Ground Cinnamon: Enhances the warm, delicious peach flavor.
Ground Nutmeg: Adds a warm, cozy flavor to the fresh peaches.
How to Make Fresh Peach Pie
Prepping this peach cream cheese pie will take about 20 minutes, and then it needs to set in the fridge for at least 4 hours before serving. It’s a great make-ahead dessert before a summer party!
Mix the Crust Ingredients: Add the graham cracker crumbs, sugar, and salt to a medium bowl and mix. Add the melted butter and mix evenly until the crumbs resemble wet sand.
Press the Crust into the Pie Plate: First, pour the crumb mixture into a 9-inch pie dish. Then, use your hands or a flat-bottomed measuring cup or glass to press the crumbs evenly into the bottom and up the sides of the dish. Set the dish in the refrigerator to chill while you prepare the cream filling.
Mix the Filling: Add the cream cheese, sugar, and vanilla to a large bowl and beat with a hand mixer or a stand mixer fitted with the paddle attachment until combined and smooth. Scrape down the sides and bottom of the bowl.
Add the Whipped Topping: Fold in about ⅓ of the whipped topping to help loosen the cream cheese mixture.
Finish Stirring the Filling: Fold in the remaining whipped topping until completely combined.
Add the Filling to the Crust: Add the cream filling to the chilled pie crust and smooth over the top. Cover the pie and chill in the refrigerator for at least 4 hours.
Make the Peach Mixture: Add the fresh peach slices, brown sugar, lemon juice, and spices to a large bowl.
Top with Peaches and Serve: Toss the peaches until evenly coated and allow them to macerate for at least 20 minutes before topping the chilled pie and serving.
Peach Pie Tips and Variations
This fresh peaches and cream pie is fabulous because it tastes amazing, is easy, and is versatile, too! Here are some simple tips and ways to change it up!
Use Homemade Whipped Topping: Instead of the whipped topping, substitute it with homemade whipped cream. To make it, whip 1 1/2 cups of cold heavy whipping cream and 3 tablespoons of powdered sugar to medium-stiff peaks. Then, use this homemade whipped cream in place of the whipped topping as directed in the recipe card.
Use Fresh Ripe Peaches: Pick the ripest peaches for this recipe! Ripe peaches are easier to pit, and if you prefer to peel them, the skin tends to pull off much easier at peak ripeness.
Tip for Tart Peaches: If your peaches are a little tart, you can remove the lemon juice and up the brown sugar by a tablespoon or two.
How to Choose Peaches: When picking peaches for this pie, look for freestone or semi-freestone peaches instead of clingstone. These varieties will be the easiest to pit!
Cutting the Peaches: Slice or dice your peaches however you’d like. I love the look of peaches in big slices, but diced peaches are easy to eat.
Making Graham Cracker Crumbs: If you want to make your own graham cracker crumbs, you can place 12 whole graham crackers in a large ziplock bag and crush them with a rolling pin until you have a fine crumb, or you can pulverize them into fine crumbs by pulsing the crackers in a food processor or blender.
Making Ahead of Time and Storing Leftovers
This dessert is super convenient because you can make everything ahead of time. Plus, leftovers store well for days!
Make Ahead: The peach topping can be made up to 24 hours before. Store in an airtight container in the refrigerator. You can also prepare the crust and cream cheese layer a day in advance, but keep the peaches separate until just before serving.
To Freeze: You can make the base of the pie, cover it with 2-3 layers of plastic wrap and aluminum foil, and freeze for up to 3 months. Thaw overnight in the refrigerator, and top with the fresh peaches just before serving. I don’t recommend freezing the pie with the peaches on top.
Storing Leftovers: Leftover fresh peach pie can be stored covered in the refrigerator in an airtight container for up to 2 days. If it has not been topped with peaches, the pie can be stored in the refrigerator for up to 5 days.
More Fresh Peach-Inspired Recipes
Peaches are my favorite fruit, and I absolutely love peach season! Give me all of the peach recipes! Here are a few of my favorites that I know you and your family will love!
Add the graham cracker crumbs, sugar, and salt to a medium bowl and mix. Add the melted butter and mix evenly until the crumbs resemble wet sand
Pour the crumb mixture into a 9-inch pie dish and use your hands or a flat-bottomed measuring cup or glass to press the crumbs evenly into the bottom and up the sides of the dish. Set it in the refrigerator to chill while you prepare the cream filling.
Cream Filling
Add the cream cheese, sugar, and vanilla to a large bowl and beat with a hand mixer or a stand mixer fitted with the paddle attachment until combined and smooth. Scrape down the sides and bottom of the bowl.
Fold in about ⅓ of the whipped topping to help loosen the cream cheese before folding in the remaining whipped topping. Fold until completely combined.
Add the cream filling to the chilled pie crust and smooth over the top. Depending on the depth of your pie dish, you may have a little extra filling. You may discard it or save it to eat on the side plain, with peaches, or with other fruit.
Cover the pie with aluminum foil or plastic wrap and chill in the refrigerator for at least 4 hours before serving.
Peach Topping
In a large bowl, combine the sliced peaches with the brown sugar, lemon juice, and spices. Allow the peaches to sit for at least 20 minutes or up to 24 hours before topping the pie and serving.
At the World AMR Congress, Britton Strickland, PhD, field application scientist for CosmosID, presented the transformative potential of microbiome science in addressing antimicrobial resistance and developing new anti-infectives. Strickland, an expert in microbiome research, detailed how advancements in this field shape strategies to combat AMR.
Strickland discusses how advancements in microbiome science can enhance our strategies for managing antimicrobial resistance, with specific methods such as examining bacterial communities through omics technologies and identifying protective or harmful bacterial mechanisms being actively explored.
Strickland emphasized that the human microbiome, including the gut and other areas, plays a crucial role in defending against pathogens. He explained, “The human microbiome, including the gut and beyond, is one of the most critical defense systems against pathogens. Traditional microbiologists have identified mechanisms like nutrient competition, microbe inhibition, antimicrobial peptides, and catabolism that help with protection.
He noted that many bacteria are not culturable in the lab and are only detectable through advanced omics technologies. “NGS and metabolomics allow us to examine the entire bacterial community within the human gut or skin and identify bacterial taxa through DNA sequencing. Metabolomics also helps profile the chemicals involved in protective or harmful mechanisms of these bacteria.”
Addressing the challenges and opportunities in developing novel anti-infectives, Strickland pointed out that while probiotics have traditionally been used to inhibit pathogens, their effectiveness is not always well-supported. “Typically, microbiome therapies have focused on probiotics, known for their effectiveness in inhibiting pathogens and preventing colonization. This concept has been recognized for thousands of years, even before bacteria were understood.”
He noted that recent interest in probiotics has led to exaggerated claims and that many probiotics struggle to establish themselves in the host. Strickland highlighted how advances in molecular techniques and reduced sequencing costs are improving our understanding of bacterial metabolites and their effects. “New therapies, such as fecal transplants and live biotherapeutic products recently approved by the FDA, are emerging.”
Strickland also discussed recent breakthroughs and projects at CosmosID, explaining how they integrate microbiome science to develop new therapies. “CosmosID uses microbiome science in several applications. Traditional diagnostic methods, which took over a week, can now identify bacteria and their antibiotic resistance within days using DNA sequencing. We apply these technologies in preclinical models to optimize products and operate in a CLIA and GXP-compliant environment with clinical samples. This allows us to analyze large-scale human data to identify bacterial taxa, track changes before and after treatment with new therapeutics, and monitor AMR genes in various environments.”
Strickland concluded by noting the broader implications of these advancements for AMR, including studying probiotic engraftment, phage therapy, and the effects of antibiotics on the microbiome. “We also study probiotic engraftment to find the best candidates for the human environment. Other applications include phage therapy, studying the effects of antibiotics on the microbiome, and understanding how local antibiotics impact the entire microbiome.”
This website may contain affiliate links and advertising so that we can provide recipes to you. Read my disclosure policy.
If you are looking for a meal plan that feeds a lot, this week is it! I have a couple of recipes that will have a lot of leftovers which is perfect for the weekend!
What’s for Dinner?
I always love meals that have a good amount of leftovers and this meal plan is perfect for that! If you don’t want to cook on Friday, save the 3 envelope roast for your Sunday meal and serve it with these mashed potatoes and rolls! Click here for more meal plans!
Homemade Hamburger Helper
A classic comfort dish that your entire family will love is this homemade hamburger helper! Cheesy noodles, meat, and delicious flavor make this recipe a go-to for any family with picky eaters!
Experience the irresistible taste of Panang curry with this easy recipe. Juicy chicken, colorful bell peppers, and aromatic Thai basil come together in a creamy coconut milk and curry paste sauce, delivering a delightful and flavorful meal.
Crack chicken casserole is creamy, cheesy, bacon-filled goodness that your family is going to want on repeat. It’s the perfect comfort food and ready in 30 minutes!
Skillet Pork Chops with Maple Dijon Vegetables is marinated Smithfield Steakhouse Mushroom Flavored Pork cut into pieces and sautéed with tender vegetables covered with a golden maple glaze. All under 30 minutes!
This 3 packet roast is my go-to for an easy but delicious Sunday dinner. Add brown gravy, Italian dressing, and ranch dressing powders to a slow cooker with your beef and then let it work its magic! It creates an ultra-tender, flavorful roast you’ll love coming home to at the end of the day.
This free weekly meal plan is just what you need to get your week started. It provides five meals that will feed 4-6 (depending on if you are feeding adults or kids), AND it includes a shopping list! With fresh new ideas and easy-to-make recipes, having a weekly menu plan will be a lifesaver.
Why Should I Meal Plan?
If you haven’t tried planning your meals ahead of time, this is going to be a game-changer for you! Here’s why I swear by meal planning:
Time Saver: No more 4:00 PM panic about dinner. With a menu plan, you know exactly what’s on the menu, what you need, and how long it takes to cook.
Money Saver: Meal planning works wonders for your wallet. When you organize your shopping list for the week, then you’ll easily spot opportunities to buy in bulk and creatively repurpose leftovers for future meals. It’s a clever approach that keeps more money in your pocket.
Bye-Bye Takeout: When your dinners are planned ahead of time and groceries are stocked, you’re less likely to hit the drive-thru. Because you are cooking at home, that means more savings and healthier eating. Win-win!
Side Dishes for Dinner
My weekly meal plans always include a printable shopping list that is measured out and ready to go. It makes things so easy!
Storing Leftovers for Meal Planning
I only meal plan Monday-Friday because we sometimes have plans over the weekend or I have leftovers that we can have to finish off the week! If you do have leftovers, make sure to store them properly in an airtight container in your fridge.
Low-cost Keystone HMO CHIP*: $45.00, $88.88, or $101.57 per child per month
Full-cost Keystone HMO CHIP*: $286.36 per child per month
How Does Keystone HMO CHIP Work?
Medical benefits are provided through the Keystone HMO CHIP network of physicians and hospitals, dental benefits are provided by United Concordia, and routine vision benefits, including coverage for eye wear and lenses, are provided by Davis Vision. Find a Keystone HMO CHIP provider.
What is the Difference Between Keystone HMO CHIP and Medicaid?
Medicaid is health coverage for individuals, including children, pregnant women, parents, and seniors who meet certain maximum income thresholds or have certain disabilities.
Keystone HMO CHIP provides health coverage for children and teens up to age 19 in families whose income is too high to qualify for Medicaid. Many of these families find Keystone HMO CHIP a great alternative to no insurance or their group insurance options. No family earns too much to enroll their child in Keystone HMO CHIP coverage!
By phone: Call the Statewide Customer Service Center for Health Care Coverage at 1‑866‑550‑4355, the Office of CHIP at 1‑800‑986‑5437, or our Member Help Team at 1-800-464-5437
By free mobile app: myCOMPASS PA
If you need help, please call the Keystone HMO CHIP Member Help Team at 1-800-464-5437 (TTY/TDD: 711). Ver esta información en español.
Not Eligible for Keystone HMO CHIP?
If your child is not eligible for Keystone HMO CHIP, you will be notified in writing as to why.
If your child appears to be eligible for Medicaid, your child’s application will be forwarded to the County Assistance Office, and you will get a letter within 30 days that tells you the application status and next steps to take.
If your child is not eligible for Medicaid, you may be eligible for financial assistance, also called subsidies, to reduce your monthly rate. Check the Tax Credit Calculator on ibx.com to see if you and your family are eligible.
You deserve the peace of mind of knowing your child has comprehensive, high-quality health insurance at a price you can afford. I encourage you to consider applying for Keystone HMO CHIP for your child.
*The premium for three or more children is three times (3x) the per-child monthly premium. Dental benefits are underwritten by Keystone Health Plan East and administered by United Concordia Companies, Inc., an independent company. Vision benefits are underwritten by Keystone Health Plan East and administered by Davis Vision, an independent company. Benefits are underwritten by Keystone Health Plan East, a subsidiary of Independence Blue Cross — independent licensees of the Blue Cross and Blue Shield Association.
At this week’s World AMR Congress, Benjamin Park, MD, senior advisor for Global Programs, Division of Healthcare Quality Promotion, CDC’s National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), participated on a panel, titled, The Role of ID Surveillance to Reduce AMR. During the conference, Park spoke to Contagion and he provided information on the agency’s involvement in AMR, including some of its initiatives and educational resources.
Contagion: In terms of the scope of the problem, can you talk about the importance of AMR as a public health issue? Park: Antimicrobial resistance is an urgent global public health threat. It has the potential to affect people at any stage of life, regardless of health status, and threatens our progress in health care, food production, and life expectancy. Antimicrobial resistance already affects all regions of the world. It is estimated to kill at least 1.27 million people worldwide each year, more than HIV/AIDS or malaria. Most of these deaths are occurring in low- and middle-income countries, especially sub-Saharan Africa.
Antimicrobial resistance happens when germs like bacteria or fungi develop the ability to defeat one or more of the drugs designed to kill them. Infections caused by antimicrobial-resistant germs can be difficult, even impossible, to treat. It can complicate nearly every health problem—from chronic conditions to infectious diseases. Modern medicine depends on antibiotics, including for joint replacements, organ transplants, cancer therapy, and the treatment of chronic diseases like diabetes, asthma, and rheumatoid arthritis.
When antibiotics and antifungals lose their effectiveness, we lose the ability to treat infections and control these public health threats. Everyone should have antibiotics and antifungals that work when they are needed.
Contagion: You are on a panel at the World AMR Congress discussing the role of infectious disease clinicians and AMR. Can you talk about the strategies providers can employ to prevent resistance? Park: CDC leads US public health efforts to combat antimicrobial resistance in support of the The US National Action Plan for Combating Antibiotic-resistant Bacteria, 2020-2025. CDC’s AR Solutions Initiative supports domestic and global programs to track infections, respond to outbreaks, and prevent infections, while building strong local relationships between public health and healthcare facilities that facilitate the implementation of actionable prevention strategies locally. Our goal is to protect people, animals, and our shared environment by preventing the spread of existing and emerging antimicrobial-resistant threats in, and into, the United States.
Prevention must be our first defense against antimicrobial resistant germs. Healthcare providers play an essential role in preventing infections and stopping the spread of germs. They can help protect patients and communities with these actions:
Follow infection prevention and control guidelines and access training resources, including screening at-risk patients when indicated.
Ensure your patients receive recommended vaccines. Talk to them and their families about:
Preventing infections
Keeping scrapes and wounds clean
Managing chronic conditions
Seeking medical care when an infection is not getting better.
Understanding when antibiotics and antifungals are needed.
Ask patients if they have recently traveled or received care in another facility. Germs can spread easily when people move.
Alert the receiving facility when transferring patients who are colonized or infected with antimicrobial-resistant pathogens.
Contagion: Can you offer an overview of the SECURE initiative and its plans to reduce AMR? Park: CDC is not involved in the SECURE initiative. World Health Organization (WHO) and the Global Antibiotic Research & Development Partnership (GARDP) lead this effort and would be more suited to respond to your question.
Contagion: What is CDC’s role in reducing AMR? Park: CDC leads the U.S. public health efforts to combat antimicrobial resistance with a global, One Health approach. The agency’s prevention efforts span healthcare settings, communities, the food supply, and the environment such as water and soil. Through CDC’s Antimicrobial Resistance Solutions Initiative, the agency invests in national infrastructure to detect, respond, control, and prevent antimicrobial-resistant infections. CDC supports efforts to slow the spread of resistance in all 50 state health departments, several local health departments, Puerto Rico, Guam, and the U.S. Virgin Islands.
CDC is also supporting innovative antimicrobial resistance projects and programs in more than 50 countries throughout the world to improve antibiotic and antifungal use, track resistance, and slow the spread of untreatable infections through infection prevention and control activities. Many of these investments, including CDC’s Global AR Laboratory and Response Network, and CDC’s Global Action in Healthcare Network, are highlighted in the AR Investment Map.
In my research into healthy alternatives to non-stick pots and pans, ceramic stood out. I’ve tried a few ceramic brands, and Xtrema cookware has become one of my absolute favorites. Not only is it beautiful, but it’s also practical and durable. Here’s why my Xtrema ceramic cookware set was well worth the investment for my […]
During her panel discussion at the World AMR Congress, Akhila Kosaraju, MD, CEO and President of Phare Bio, addressed strategies for modernizing incentive structures in antimicrobial development. The panel addressed the main barriers to antimicrobial development and explored innovative approaches to overcome these challenges.
One of Kosaraju’s key points was the concept of the “two valleys of death” in drug development.
The First Valley of Death: This is the gap between early-stage discovery and clinical trials. It represents the high-risk phase where a new drug has to transition from initial research and development (R&D into more advanced stages, including preclinical studies and clinical trials. This phase is challenging due to the high cost of development, technical uncertainties, and the significant risk of failure.
Kosaraju explained, “In terms of how we’re addressing it, in addition to the efficiencies and the precision and the opportunities that come from the AI platform itself, we’re also using a nonprofit model. So the reason that’s important is that we’ve decided to have this part of the valley of death be funded with philanthropic and grant funding, and by doing that, we can de-risk our compounds, push them forward through preclinical development, and then have those conversations with venture capitalists and Big Pharma when these compounds are much closer to the clinic and where the risk-reward is rebalanced.
The Second Valley of Death: This occurs after a drug has been approved and involves the challenge of commercialization. Even if an antibiotic successfully makes it through clinical trials and receives approval, it may still face difficulties in succeeding commercially. This can be due to factors such as inadequate market incentives, low profitability compared to blockbuster drugs in other fields, and difficulties in achieving market penetration
Kosaraju’s approach to overcoming this challenge involves, “ moving the entire field forward with what’s called pull incentives, so subscription models or other ways to really reinvigorate the marketplace for antibiotics, you then have more activity on the licensing co-development side. You have more investment in preclinical pipelines commercially, so it trickles all the way to early stage development. And so we think it’s absolutely critical that not only are we addressing the first valley of death in early stage R&D, but that this second, you know, pull incentive necessity is addressed as well.”
Kosaraju also discussed how AI and deep learning are impacting antibiotic discovery and development. “AI is particularly suited for this because it can help identify and prioritize novel chemical spaces for drug discovery. By focusing on finding new mechanisms of action, AI addresses the core issue of AMR, which is the overuse of old antibiotics leading to increased resistance.
Since 2017, Phare Bio has achieved significant milestones. Kosaraju brings awareness to these accomplishments, “discovering two novel classes of antibiotics, published in Cell and the other in Nature Chemical Biology. We are also incorporating new parameters into our AI platform, such as drug toxicity, oral formulation, and half-lives, which could lead to significant advancements,” she explains. “A proof of concept in Nature last December on this idea, suggesting that AI could lead to tailored drug discovery processes.
Addressing the challenges in antibiotic development requires push and pull incentives. Kosaraju emphasized the role of government policies, “the first key part is having some marketplace. If you have an approved product, especially one that has a novel mechanism of action against a high-priority pathogen that should be incentivized and rewarded.”
Legislation like the PASTEUR Act can stabilize the market for novel antibiotics by separating sales volume from pricing, while increased government grants for early-stage innovation are crucial for breakthrough discoveries.
In conclusion, addressing the challenges in antibiotic development requires both innovative strategies, such as AI-driven discovery and nonprofit funding models, and supportive government policies. These measures are important for revitalizing the antibiotic pipeline and combating antimicrobial resistance effectively.
This website may contain affiliate links and advertising so that we can provide recipes to you. Read my disclosure policy.
This chicken tetrazzini casserole is packed with delicious flavors and textures. It has hearty chicken, tender mushrooms, peas, and pasta, all tossed in a creamy, rich sauce. The casserole is topped with crispy, buttery breadcrumbs and a sprinkle of Parmesan cheese with the most irresistible crunch and flavor.
Reasons You’ll Love This Recipe
Make-Ahead: This is the perfect dish to make ahead and throw in the oven right before dinner. It makes dinner time quick and stress-free!
One-Dish Meal: You get your protein, veggies, and pasta all in one satisfying dish. You won’t need to make any other sides!
Quick and Easy: Chicken tetrazzini casserole is so simple to make! Boil the paste, sauté the veggies, stir up the sauce and add the chicken!
Ingredients Needed to Make Chicken Tetrazzini Casserole
This casserole only uses a few ready-made ingredients. Plus, with its simple ingredients and easy-to-follow instructions, dinner time will be smooth and stress-free! Scroll to the bottom of the page for exact measurements.
Cooked and Cubed Chicken: The main protein source that gives the dish a hearty, meaty texture and savory flavor.
Spaghetti Pasta: The base of the casserole that perfectly absorbs the creamy sauce.
Olive Oil: Used to sauté vegetables, adding healthy fat.
Diced Mushrooms: Absorb the wonderful savory flavors and gives a nice texture.
Minced Garlic: Gives the dish a warm, comforting savory flavor.
Frozen Peas: Add a pop of color, texture, and sweet flavor.
Flour: Helps thicken the sauce.
Cream of Chicken Soup Cans: Provide moisture and flavor to the casserole.
Hald and Half: Adds a smooth, creamy texture and delicious flavor.
Chicken Broth: Gives the casserole moisture and adds a depth of chicken flavor.
Salt and Pepper: To Taste!
Parmesan Cheese: Provides a sharp, nutty flavor.
Italian Bread Crumbs: Adds flavor and texture for a crunchy topping.
Melted Butter: Allows the topping to become browned and crunchy.
How Do You Make Chicken Tetrazzini?
Making chicken tetrazzini casserole is simple. I love being able prep it in the morning or the night before so that when it’s time to eat, I can pop it in the oven, and dinner is served.
Prep: Preheat the oven to 350 degrees. Spray a 9×13-inch casserole dish with cooking spray and set aside. In a large pot, cook the pasta according to the directions until al dente. Drain, then place in the prepared baking dish.
Sauté and Stir: In a medium-sized saucepan, add olive oil, mushrooms, garlic, and peas. Cook until tender, then whisk in the flour and cook for another minute.
Make the Sauce: Add the cream of chicken soup, heavy whipping cream, and chicken broth to the saucepan. Add salt and pepper to taste. Let simmer until it starts to thicken, then add the chicken and mix to incorporate.
Combine: Add the sauce to the spaghetti and toss until coated. Spread in your 9×13-inch pan.
Make the Topping: Mix the parmesan cheese, bread crumbs, and butter in a bowl, then spread the mixture on top of the casserole.
Bake: Bake for 30-40 minutes until heated through, and the bread crumbs are brown on top.
Tetrazzini Tips and Variations
The great thing about this chicken tetrazzini casserole is you can make it to suit your tastes. Here are some ideas to get you started.
Vegetables: You can leave out the peas or the mushrooms or both. You could also add other veggie like onions, broccoli, bell pepper, potatoes or any of your favorite veggies.
Protein: This is a great casserole to make with leftover turkey. Replace the chicken with your leftover turkey from Thanksgiving. You could also use ham, pork, beef, or sausage.
Condesned soup: You can replace the cream of chicken with cream of mushroom soup cans. You can also replace the condensed soup and use my homemade cream of chicken soup.
Freezer Meal Instructions
You can make chicken tetrazzini casserole as a freezer meal! I like making a couple of batches, freezing them and pulling them out as I need. After you have gone through step 5, cover it with plastic wrap and then aluminum foil, and freeze. Then, when you are ready to have it for dinner, follow the instructions below!
Heat the oven to 375 degrees Fahrenheit.
Cover the dish with foil, place it directly into the preheated oven from the freezer, and bake for 50-60 minutes until the dish is heated completely through.
Remove the foil in the last 10 minutes of baking.
How to Store Leftover Chicken Tetrazzini
Leftover casserole is especially good for reheating the next day. By then, all of the flavors have melded together, and your kids will love having something warm and hearty after school.
Refrigerator: Store leftovers in the fridge in an airtight container for up to 5 days.
Reheat: Warm individual servings in a microwave-safe dish for 30-seconds at a time until heated through.
More Chicken Casserole Recipes
Casserole cooking is a must at my house. After all, making one dish that includes veggies, protein, and a hearty base makes my life easier and my family’s stomachs happy! Here are some of my favorite quick and easy recipes!
Preheat oven to 350 degrees. Spray a 9×13-inch casserole dish with cooking spray and set aside. In a large pot cook pasta according to the directions, and cook until al dente. Drain and place in the prepared baking dish.
Add olive oil, mushrooms, garlic, and peas in a medium-sized saucepan. Cook until tender. Whisk in the flour and cook for an additional minute.
Add the cream of chicken soup, heavy whipping cream, and chicken broth to the saucepan, add salt and pepper to taste. Let simmer until it starts to thicken. Add the chicken and mix to incorporate.
Add the sauce to the spaghetti and toss until coated. Spread in your 9×13-inch pan.
Mix the parmesan cheese, bread crumbs, and butter in a bowl. Spread the mixture on top of the casserole.
Bake for 30-40 minutes until heated through, and the bread crumbs are brown on top.
Originally Posted Nov 9, 2017 Updated September 4, 2024
I’ve spent hours experimenting with organic hair care recipes like homemade conditioner and dry shampoo. This time it was natural hair dye recipes. My family is used to my skincare experiments, but this one came with its fair share of laughs. I walked around with some concoction of herbs on my head for weeks!
I’d experimented with natural hair lightening in the past but hadn’t tried dark or red shades (since I have blonde hair). I found a few willing dark-haired friends to test other formulas. Many wasted herbs and a bunch of randomly colored streaks later, I figured out some good dark and red options as well!
Conventional Permanent Hair Dye
Not sure why you’d want to use herbal hair dyes with natural ingredients? Read the label of conventional hair color and you’ll see parabens, silicone, and sulfate to name a few things. Some permanent hair color options also have resorcinol. This chemical helps the color bond to hair, but it’s also known to cause skin irritation and thyroid damage (plus other things).
Then there’s the P-phenylenediamine (PPD) used alongside peroxide. Not only is it used to make kevlar, but it can also cause your cell’s genes to mutate. Not something I want right next to my brain! Plant-based organic ingredients aren’t quite as strong, but they’re a great alternative if you want a clean hair dye option.
Over time chemically treated hair can become brittle and lead to hair loss. By dying it at home you not only avoid harmful chemicals, but you don’t have to make frequent trips to the hair stylist for a root touch-up.
DIY Natural Hair Dye Without Chemicals
Since these are natural colors from herbal pigments they’ll create natural hues on your hair. You won’t get artificial colors like hot pink or platinum blonde.
The blonde/light recipes will permanently lighten hair since they naturally bleach it. The red and dark hues will leave a temporary tint for a few weeks (depending on how often you wash it). Time in the sun helps set all of the hues and brings out natural highlights.
Note: I haven’t tried all of these natural hair color methods on previously dyed or chemically treated hair. Always test a small swatch of hair (I put a little on my skin too) to test for results and rule out any allergic reactions. Also, don’t use these hair dye recipes on hair that’s been chemically treated in the last 6-8 weeks.
Herbs for Light Hair
If your hair is ash blonde, light blond, or even dark blond, you can get natural highlights with these herbs. They help to lighten and enhance for natural hair coverage. I’ve tried several basic herbal variations including:
Chamomile tea – I use a really strong brew and spray or pour it on my hair and leave it for several hours. Sitting in the sun during this time enhances the lightening effect.
Lemon juice – Freshly squeezed lemon juice also produces natural highlights. Spray and brush lemon juice through hair and leave it on for several hours in the sun).
Chamomile tea rinse– Use it as a rinse at the end of each shower and leave it in your hair! This produces smooth, silky hair and naturally lightens it over time.
For a stronger and faster effect, I’ve used the recipe below. It’s left my hair very blonde, easy to work with, and not yellowy/brassy at all.
Herbs to Dye Red Hair
These will create a red/dark strawberry blonde tint in lighter hair and an auburn tint in darker hair. The effects are cumulative, so extended use over time creates a more vibrant red. The easiest thing is to make it part of your hair care routine if you want continual red hair.
Calendula flowers or fresh marigold petals from your garden. Don’t worry, you can buy these (unsprayed) if you don’t have any.
Hibiscus petals
Herbs to Dye Brown Hair
It’s easiest to darken hair that’s already light brown or darker, though these colors will darken blonde tones as well. Used as a rinse, these herbs will also darken grey hair over time. The more they’re used, the darker the results.
For a faster, more dramatic effect, use a henna color like black, dark brown, or mahogany. For a slower or more gentle tone, use these herbs:
Herbs to Dye Dark Brown Hair or Black Hair
If you have very light hair, it will be difficult to get really dark hues with just herbs, though with enough patience, it can be done. Indigo also works for this. I’ve listed herbs that work, and you can use any combination.
As always, test on a small section of hair before using. Henna hair colors provide dark results that last longer, but if you want to go dark gradually, these are the recipes I’ve tried:
Black walnut powder– Use as a rinse in the shower for hair and dry in the sun if possible. This will create VERY DARK hair, especially if you have dry or color-treated hair. It also provides the darkest coverage for grey hair. Repeat daily or as needed to darken and maintain dark shade.
Strong black tea – Use strong brewed black tea as a final rinse to darken any color hair. This is also nourishing for the hair and will provide a temporary darkening effect on most hair types. Repeat as necessary to get the desired shade and sun-dry if possible.
With any of these herbal hair colors, make sure to test on a small part of your hair first. Especially with color-treated hair and especially with the henna colors as they have more lasting effects.
Experiment with any of the above to get the right mix for your hair! I’ve included some recipes below for you to try.
Natural Hair Dye Recipes
Tried and true recipes for herbal color hair with natural herbs. Works for all different hair colors and helps nourish your hair and scalp.
Author: Katie Wells
Light Hair Color Ingredients
Red Hair Color Ingredients
Brown Hair Color Ingredients
Dark Brown Hair or Black Hair Color Ingredients
Light Hair Color Instructions
Mix all ingredients in a spray bottle or other small bottle.
Shake well and spray or pour it onto the hair. Brush it through to ensure even coverage.
Go outside in the sun for 1-2 hours, then rinse your hair. I suggest putting this in your hair and doing a kettlebell workout in the sun for maximum benefit!
This can be used several times a week until the desired color is reached. You can also use this as a rinse at the end of a shower (and then lightly rinse with water) though it will take longer to have an effect. This will not have an overnight dramatic effect. However, when I put it in my hair before gardening in the sun for a few hours I noticed a difference.
This spray will stay fresh for several days in the fridge.
Red Hair Color Instructions
In a small pan, bring the water to a boil.
Reduce to a simmer and add the calendula/marigold and hibiscus.
Simmer for at least 30 minutes with the lid on.
Remove from heat and when cool, strain herbs out, making sure all small pieces are removed (I use cheesecloth).
Use as a final hair rinse at the end of each shower. Dry hair in the sun if possible.
Repeat daily until the desired shade is achieved and then every few days to maintain.
Store the liquid in the refrigerator for up to 5 days.
Brown Hair Color Instructions
In a small pan, bring the water to a boil.
Reduce to a simmer and add the herbs.
Simmer for at least 30 minutes or until the water is very dark.
Remove from heat and when cool, strain herbs out, making sure all small pieces are removed (I use cheesecloth).
Spray or brush into hair about an hour before showering each day, then shampoo as normal. Can also use as a rinse and leave on at the end of each shower.
Repeat until desired color is reached. It has a cumulative effect and you probably won’t notice much difference the first few days. The herbs in this mix are also great for getting rid of dandruff and for increasing hair growth!
Store the liquid in the refrigerator for up to 5 days.
Dark Brown Hair or Black Hair Color Instructions
Tie the black walnut powder in a tea bag or cheesecloth bag.
Place in a quart mason jar and add the water.
Steep for at least 6 hours or overnight.
Use as a rinse in the shower for hair and dry in the sun if possible. This will create VERY DARK hair, especially if you have dry or color treated hair. It will also provide the darkest coverage for grey hair.
Repeat daily or as needed to darken and maintain dark shade.
You can also use strong brewed black tea as a final rinse to darken any color hair. This is also nourishing for the hair and will provide a temporary darkening effect on most hair types.
Repeat as necessary to get desired shade and sun-dry if possible.
Always pre-test on a strand of hair before doing the entire head to check the color and rule out an allergy.
Some sources recommend against prolonged internal use of black walnut hull. This hair rinse only uses it externally, but check with your natural health care practitioner if you have any concerns.
Semi-permanent Natural Hair Dye at Home
You can use henna hair color if you want faster and more permanent results. I’ve purchased from Morrocco Method with great success. They have excellent products, and the results are dramatic. I also like that they’re natural and cruelty-free.
They have a lot of color variations with red hues to dark brown to black. The results last for several months or longer if you wash your hair less often or use a gentle natural shampoo. They don’t offer complete grey coverage for grey or white hair. However, it will noticeably darken it to help cover grey hair naturally.
Important Note: Henna can react with the ammonia in conventional hair dye. This turns hair orange or even green! If you have chemically treated your hair recently, wait at least 6-8 weeks before trying henna. Before applying the package, test on a small section of hair before using it on the whole head!
Indigo For Darker Hair
Indigo is a natural, vegan plant dye used in Ayurvedic traditions to dye hair and fabric. It can be mixed with henna for a medium-brown to dark-brown shade. In the right proportions, it can even dye hair a dark inky black. Morocco Method details how to use it here.
Have you ever used natural hair dye to color your hair? Let me know below!
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